https://en.wikipedia.org/wiki/Agmatine#Opioid_liability
Systemic agmatine can potentiate opioid analgesia and prevent tolerance to chronic morphine in laboratory rodents. Since then, cumulative evidence amply shows that agmatine inhibits opioid dependence and relapse in several animal species.
Has any of you humans tried this?
I'm afraid this supplement had no noticeable effect in my case. On the other hand, I don't really respond (any longer?) to oxycodone or norco, so maybe it works for someone who does.
Note that I didn't really take much oxycodone. It's been 7 weeks since my last surgery, and for the past few weeks, I've been taking at most 2 oxy's per week, before PT with Mike. It just doesn't decrease the pain noticeably (compared to THC as a benchmark).
Quote from: Johnson1111 on May 31, 2018, 08:25:10 PMAll it does is get you high
What "it" gets you high? Agmatine didn't get me high, and neither did oxycodone or norco.
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