And here is one on HUMANS. 3 acondroplastics so not normal cases..
To be noted that the distraction was of 1mm a day (4 times a day of 0.25mm every 6 hours) for a total elongation of 10cm.
Result show alot of muscle damage and poor adaptation (as opposed to what was seen in the goats)
http://www.bio.unipd.it/bam/PDF/5-2/Scelsi.pdf
Quote from: TIBIKE200 on March 18, 2016, 06:19:17 PMThere is one big flaw with your logic though... Human cells arent bigger than rabbit cells... Just like elefant cells arent bigger than human cells.. Thus the damage to a single cell would be the same. It also depends on the sarcomer length (the "muscle functional unit").
The only difference between humans, rabbits and elefants is the numebr of cells but not the size
What? This is what I said: "assume that human and rabbit muscle cells are the same size"
If they are the same size, and then a human tibia, which is 4 times longer than a rabbit tibia, should have about 4 times more muscle cells length-wise. Since the stretching is divided among 4 times more cells, each cell stretches less and is at less risk for damage.
Quote from: TIBIKE200 on March 18, 2016, 06:19:17 PMThere is one big flaw with your logic though... Human cells arent bigger than rabbit cells... Just like elefant cells arent bigger than human cells.. Thus the damage to a single cell would be the same. It also depends on the sarcomer length (the "muscle functional unit").
The only difference between humans, rabbits and elefants is the numebr of cells but not the size
What? This is what I said: "assume that human and rabbit muscle cells are the same size"
If they are the same size, and then a human tibia, which is 4 times longer than a rabbit tibia, should have about 4 times more muscle cells length-wise. Since the stretching is divided among 4 times more cells, each cell stretches less and is at less risk for damage.
I would guess that having flexible legs pre-op would reduce the damage like in those studies. Especially if you do a smaller amount, say 3.5cm instead of something crazy like 8cm. When you get to like 6-8cm I would imagine your muscles will get "stretching damage". Does anybody know at what length the body has to produce muscle that is stretched?
Quote from: applesandoranges on March 19, 2016, 03:49:06 AMI would guess that having flexible legs pre-op would reduce the damage like in those studies. Especially if you do a smaller amount, say 3.5cm instead of something crazy like 8cm. When you get to like 6-8cm I would imagine your muscles will get "stretching damage". Does anybody know at what length the body has to produce muscle that is stretched?
Yep. This is why flexibility is much much much more important than muscle mass. About your safety length, it wasnt discussed... But on the goat study, they said that damage begin after 20% of original length
Great research TIBIKE.
To be honest, I always wonder why people care so much about minor muscle deterioration though.
I've never been able to play sports. The last competitive sports team I made it onto I was 11 years old.
I don't get what people are thinking they are losing out on.
How many professional or semi-professional 5'4"-5'7" athletes do we have on this site? 
For me, the only reason I hesitate to do the surgery is the requirement to be off work for 6 months. I don't know how to manage that. Otherwise, losing 5-20% of your "athleticism" due to muscle scarring is insignificant to me.
As long as I could walk at a normal pace after, and ideally not develop premature arthritis due to misalignment of my joints, nothing would change for me.
Bump for interesting discussion on lengthening rate.
A rate of lengthening of 1.75mm when risk of premature consolidation is possible?
Quote from: onemorefoot on March 13, 2017, 07:19:08 AMA rate of lengthening of 1.75mm when risk of premature consolidation is possible?
Possible? Yes. Highly likely to permanently damage your soft tissue? Yes.
Of course you could get a huge injury and have way worse muscle from it say a car crash, oh isn't LL needed for legs that aren't the same length after one? Just saying this surgery isn't that insane.
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