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Posted on Jun 9, 2018, 11:16 am
#101

Could the slower callous formation be due to his older age than say someone in their late teens or 20s? I know it is a possible occursnce regardless but maybe people in 40s should lengthen slower in comparison?

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Posted on Jun 9, 2018, 11:28 am
#102

Quote from: Rocky on June 09, 2018, 10:28:30 AMImportant

Dear members

I would kindly and sincerely ask you to not use any bad words in my diary. My family reads this diary every day, including my 6 years old kid who is learning how to read.

I know that I can't demand or dictate it, but I am asking sincerely and kindly to select your words carefully which is suitable for such a respectable forum and is somehow "family friendly".

Again, I can't force you to do so. Its just a friendly ask from a carrying dad.

Thank you for your understanding and may God protect and bless you all.

That's understandable. I'll be more mindful too.

Quote from: Johnson1111 on June 09, 2018, 11:16:35 AMCould the slower callous formation be due to his older age than say someone in their late teens or 20s? I know it is a possible occursnce regardless but maybe people in 40s should lengthen slower in comparison?

That's not a question for any of us to answer... We don't have the qualifications. The science on this is pretty mixed.

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Posted on Jun 9, 2018, 3:37 pm
#103

Quote from: myloginacc on June 09, 2018, 11:28:28 AMThat's understandable. I'll be more mindful too.

That's not a question for any of us to answer... We don't have the qualifications. The science on this is pretty mixed.

Thank you myloginacc. May God protect you.

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Posted on Jun 9, 2018, 3:45 pm
#104

About Stem Cells Treatment

Dear members

Since we had some discussions around stem cells treatment, I consulted Dr. Jamal during his visit to educate myself and understand how he actually does it.

I thought till today that I knew what it was. But I discovered that I have a lot to learn about the topic.

Let me explain to you for those who might be interested in this topic.

The procedure is as follow:

1) Stem Cells harvesting: When the bone is cut during the surgery, the doctor takes stem cells samples from the bone. The stem cells are not hard bone tissues. Its actually a liquid they suck out in small doses.

2) Stem Cells maintenance: The stem cells are sent to the laboratory where they will be treated, kept in specialized containers and maintained for several months or years.

3) Stem Cells treatment: With the stem cells you can develop any tissue in the body (muscles, nerves, bones, callous, etc.). At the laboratory, they prepare 3 doses from the taken original stem cells:

3a) Osteoclast (bone): This will be injected between bone gaps to create callous.

3b) myoblast (muscles): This will be injected in places where muscles could have been damaged to re-create new muscles.

3c) Neuroblast (nerves): This will be injected in the places where the nerves might have been damaged to re-create new nerves.


3d) Original Stem Cells liquid:
And lastly the original stem cells liquid will be injected in the patient vessel, e.g. the arm vessel, and not in the bone area as I thought earlier.

4) PRP: As an extra service, he includes also Platelet-Rich Plasma (PRP) Injections at the end of the course for better health.

Dr. Jamal performs also other old school treatments such as bone grafting or implants and mix it with the new stem cells treatment.

The interesting part is, with the stem cells taken from your body, as mentioned earlier, you can create any tissue in the human body. In the laboratory they can create a full human bone that can be inserted directly in the gap after the lengthening. It is costly but it can be done.

That's why non union can be fixed with today's new technology without issues. The thing is, not so many LL doctors are specialized in stem cells treatment or tissue re-creation from scratch. Few LL Surgeons around the world apply this treatment as part of the lengthening program. They can probably be counted on few fingers.

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Posted on Jun 9, 2018, 4:29 pm
#105

Day 48 Update:

Couple of days ago I started noticing that when I lay down in bed for long time, my right knee becomes very tight and it hurts.

I was telling the physio therapist about it yesterday during the massage time.

In today's session, the physio therapist brought a very tiny needle with insulin syringe liquid. I got small injections in the right knee. Magically the pain in the knee vanished in about 3 hours. I feel much better now.

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Posted on Jun 9, 2018, 10:20 pm
#106

Congratulations on your progress. It was really interesting to read how they do the stem cell treatment. I believe that Ukraine is the leading country when it comes to stem cell research development. I remember last year reasearching into Emcell which is the most advanced (to my knowledge) stem cell research developement clinic in the world. This is largely due to the fact that a lot of western countries put a lot of bans/restrictions on stem cell research for ethical reasons, which Ukraine is not affected by.

Even so please remember that the stem cell/ bone graft can come at a costly price (and I’m not talking just money) please be weary when lengthening so quickly as contrary to your belief, I believe, after reading a lot of other diaries on here that callus’s should be showing by now.

Good luck and I wish you the best possible ending to your journey  My LL Journey - Dr. Jamal Abu Nemer, Kiev

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Posted on Jun 9, 2018, 10:38 pm
#107

Quote from: Rocky on June 09, 2018, 03:45:10 PMAbout Stem Cells Treatment

Dear members

Since we had some discussions around stem cells treatment, I consulted Dr. Jamal during his visit to educate myself and understand how he actually does it.

I thought till today that I knew what it was. But I discovered that I have a lot to learn about the topic.

Let me explain to you for those who might be interested in this topic.

The procedure is as follow:

1) Stem Cells harvesting: When the bone is cut during the surgery, the doctor takes stem cells samples from the bone. The stem cells are not hard bone tissues. Its actually a liquid they suck out in small doses.

2) Stem Cells maintenance: The stem cells are sent to the laboratory where they will be treated, kept in specialized containers and maintained for several months or years.

3) Stem Cells treatment: With the stem cells you can develop any tissue in the body (muscles, nerves, bones, callous, etc.). At the laboratory, they prepare 3 doses from the taken original stem cells:

3a) Osteoclast (bone): This will be injected between bone gaps to create callous.

3b) myoblast (muscles): This will be injected in places where muscles could have been damaged to re-create new muscles.

3c) Neuroblast (nerves): This will be injected in the places where the nerves might have been damaged to re-create new nerves.


3d) Original Stem Cells liquid:
And lastly the original stem cells liquid will be injected in the patient vessel, e.g. the arm vessel, and not in the bone area as I thought earlier.

4) PRP: As an extra service, he includes also Platelet-Rich Plasma (PRP) Injections at the end of the course for better health.

Dr. Jamal performs also other old school treatments such as bone grafting or implants and mix it with the new stem cells treatment.

The interesting part is, with the stem cells taken from your body, as mentioned earlier, you can create any tissue in the human body. In the laboratory they can create a full human bone that can be inserted directly in the gap after the lengthening. It is costly but it can be done.

That's why non union can be fixed with today's new technology without issues. The thing is, not so many LL doctors are specialized in stem cells treatment or tissue re-creation from scratch. Few LL Surgeons around the world apply this treatment as part of the lengthening program. They can probably be counted on few fingers.
All these offer nothing if you have a more than 2-3 cm gap. If you continue at the distraction rate you are doing now you'll have a big gap at 5cm (not even more than that) that won't bridge, so in a few words, a malunion.
Malunions of that amount cant be treated with nothing else except from shortening the bone.

So for a last time, keep a serious eye on the calous. If it stays almost invisible stop lengthening.
Otherwise you are going to be in trouble, no matter what Nemer says.

Keep strong!

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Posted on Jun 10, 2018, 2:59 am
#108

Quote from: Body Builder on June 09, 2018, 10:38:27 PMAll these offer nothing if you have a more than 2-3 cm gap. If you continue at the distraction rate you are doing now you'll have a big gap at 5cm (not even more than that) that won't bridge, so in a few words, a malunion.
Malunions of that amount cant be treated with nothing else except from shortening the bone.

So for a last time, keep a serious eye on the calous. If it stays almost invisible stop lengthening.
Otherwise you are going to be in trouble, no matter what Nemer says.

Keep strong!


Dear Body Builder

I guess you skipped few lines that would have clarified your concern.

Stem cells technology can offer you what you are talking about. In worst case scenario a full human bone from your own body cells can be created in the lab, among other body tissues. It is costly but doable.
 
Since this is probably a new technology that no one has ever addressed in this forum in depth, I guess we (whom are interested in going deep in this topic) educate our self a little bit and consult experts before giving qualified advises to other members on particularly that topic. That includes me by the way.

May God bless you with wisdom.

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Posted on Jun 10, 2018, 7:54 pm
#109

Quote from: Rocky on June 10, 2018, 02:59:32 AM
Dear Body Builder

I guess you skipped few lines that would have clarified your concern.

Stem cells technology can offer you what you are talking about. In worst case scenario a full human bone from your own body cells can be created in the lab, among other body tissues. It is costly but doable.
 
Since this is probably a new technology that no one has ever addressed in this forum in depth, I guess we (whom are interested in going deep in this topic) educate our self a little bit and consult experts before giving qualified advises to other members on particularly that topic. That includes me by the way.

May God bless you with wisdom.

We have addressed this in the past. But I think you mentioned Jamal's approach being stem cell stimulation at the end of the treatment.

This is what it entails:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492338/

QuoteDistraction osteogenesis (DO) mobilises bone regenerative potential and avoids the complications of other treatments such as bone graft. The major disadvantage of DO is the length of time required for bone consolidation. Mesenchymal stem cells (MSCs) have been used to promote bone formation with some good results.

[...]

Conclusion

The majority of studies reported that the transplantation of MSCs enhanced bone consolidation or formation in DO.

Dr. Donghoon Lee also offers this approach. That is, stem-cell therapy.


This is a different beast from tissue engineering a human bone.

I do not believe it has ever been done to treat a human being with any kind of limb trauma.

This is the stage we're currently at:

https://www.wired.co.uk/article/lab-grown-bone-biomedical-engineering-osteoporosis-amputees

QuoteThis technique will be tested on humans in 2020, when an NHS plastic surgeon will deliver a small bit of lab-grown bone into a patient's hand. Once this is in motion, Dalby says, the team will work towards growing the bone putty and adding the scaffolding within a week.
Based on what I know, only a similar, experimental medical procedure has been successfully done: it was by an Israeli biomedical startup earlier this year.

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Posted on Jun 10, 2018, 11:39 pm
#110

Quote from: Rocky on June 10, 2018, 02:59:32 AM
Dear Body Builder

I guess you skipped few lines that would have clarified your concern.

Stem cells technology can offer you what you are talking about. In worst case scenario a full human bone from your own body cells can be created in the lab, among other body tissues. It is costly but doable.
 
Since this is probably a new technology that no one has ever addressed in this forum in depth, I guess we (whom are interested in going deep in this topic) educate our self a little bit and consult experts before giving qualified advises to other members on particularly that topic. That includes me by the way.

May God bless you with wisdom.
Nothing on the present times can fix a gap of 4-5+ cm.
They havent done it on UK which is a far superior country in terms of medical things, if you think that Nemer can do it so risk it.
I've done my duty to warn you, anything else is up to you.

Stay strong.

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