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Posted on Sep 11, 2020, 10:28 am
#1

This European project will be completed in 2022. Could it bring to growth plate reopening in adults?

https://cordis.europa.eu/project/id/843717/it

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Posted on Sep 11, 2020, 11:05 am
#2

Thank you. I think the same thing. I guess the least we can expect as a community is a safe alternative to limb lengthening or, at any rate, a real and substantial improvement of current lengthening techniques: we have to demand and fight for much safer cll techniques involving for example laser osteotomies (https://aot.swiss/en/carlo/), stem cells, nanorobots and no metal implants.

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Posted on Sep 11, 2020, 11:07 am
#3

 Reopening growth plates Thank you, Bruce. I cherish you too.

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Posted on Sep 11, 2020, 11:35 am
#4

Quote from: O_99 on September 11, 2020, 11:15:41 AM+1

Do you know anything about this? http://www.limblengtheningforum.com/index.php?topic=65449.0
Is it safe to take c60?

I read it some time ago. I don’t know much about it, I know that fullerenes can be toxic, but trying C60 olive oil shouldn’t be so dangerous. However I’m a little bit skeptical about results, I doubt it can really increase height.

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Posted on Sep 11, 2020, 11:36 am
#5

Quote from: ghkid2019 on September 11, 2020, 11:17:45 AMThank you for this Antoniō. Instills hope in me.

You’re welcome. Reopening growth plates

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Posted on Sep 11, 2020, 11:45 am
#6

Quote from: YungGud on September 11, 2020, 11:28:39 AMohh,i would love to get taller without CLL,even in 2022

Yes, if we manage to reopen growth plates growing taller for adults should be easy. Now there are many growth-promoting substances that are safer than HGH. Indirubin-3′-oxime is one of them.
I quote from this source about indirubin-3′-oxime: https://www.researchgate.net/publication/335759824_Indirubin-3'-oxime_stimulates_chondrocyte_maturation_and_longitudinal_bone_growth_via_activation_of_the_Wntb-catenin_pathway
“Longitudinal growth of bones is driven by the proliferation and differentiation of cartilage cells in the growth plate. Choi and colleagues screened a chemical library and identified a compound derived from traditional Chinese herbs, which efficiently promotes this bone growth process in cultured cartilage cells and in the tibias of three-week-old mice. This compound appears safe, suggesting a potentially better avenue for promoting height growth.”

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Posted on Sep 11, 2020, 12:03 pm
#7

Yeah, I took a look at that. It seems really promising to me, but it is a complex and potentially dangerous drug stack that I wouldn’t test directly on humans. Very interesting, but it needs a lot of testing.

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Posted on Sep 11, 2020, 2:35 pm
#8

Quote from: Kenda on September 11, 2020, 01:30:56 PM
I really hope that they find alternatives that are much faster than this surgery! but the thing is growth plates are no longer existent in my age of 21 for example , so what would they open? Reopening growth plates 
it transforms from cartilage to solid bone once it closes and in my case that was very early due to hormone or endocrine imbalance !!

This is a really good question and I’m sorry I don’t have a precise answer. However, if this European project succeeds in reactivating damaged growth plates in children, I guess it wouldn’t be so difficult to reactivate them also in adults, because the bone bar in children with damaged growth plates is similar to the barrier in the adults’ long bones and also because adults too seem to have stem cells that maybe could reactivate growth plates https://www.nature.com/articles/d41586-019-00527-w

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Posted on Sep 11, 2020, 7:05 pm
#9

Quote from: levsfri on September 11, 2020, 05:30:20 PMSeems too good to be true in reality for at least another 10 years tbh, likely way more

Maybe you’re right, maybe not. I think that if we join the forces and fund research, good results would come out not long from now.

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Posted on Sep 11, 2020, 10:23 pm
#10

Quote from: Body Builder on September 11, 2020, 07:07:12 PMAnd you are very optimistic.

Optimism and pessimism are relative concepts in a world where it doesn’t take much to revolutionize a field in a positive (iPhone?) or negative (COVID-19?) way.
However, it’s a fact that Oviedo University is leading a research to regenerate injured growth plate in children. This project will be completed in 2022. If they manage to regenerate damaged growth plates in children, it is likely that the same technique or a similar technique works for adults. These are all facts. It could happen or not, they could succeed or not. But it’s not impossibile, we might have a solution within 2022.

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