What is the future of limb lengthening? What do you hope to see happen?

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Quote from: Drop-Loud on September 13, 2020, 06:48:38 PMHi Antoine,

Thanks for sharing these links. We need to find a way to contact this Korean company to have more info about their drug.

You’re welcome Drop-Loud. You’re right, we should find a way to contact them. I‘ll try. If I succeed, I’ll let you know.

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Quote from: ghkid2019 on September 13, 2020, 07:08:33 PMWhat even is the point of these compounds? We already fkin know how to elongate the growth plate. It's called human growth hormone. The only thing we give a shiet about is reopening growth plate. None of this shiet will do that, they are just an equivalent to hgh. They might even be better than hgh but again, WE DONT CARE, that's not the problem with gaining height as an adult with FUSED PLATES.

UNTIL We find something that opens growth plates again, all this shiet is borderline useless. We are not kids with growth plates, we are adults with ossified ephyphiseal lines already. It's goddamn bone...

I largely agree with you. However, there could be a very little chance that this compound works also for adults, maybe together with LPP. I don’t think so, but it never hurts to try. The patent of the Korean compound ambiguously says that the product is “prescribable to various age groups”.
Of course our priority should be giving back growth plates to adults.

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Hi Antoine, thank you. I hope you will have more success than me. LPP and Indirubin are the most promising alternatives we have at the moment if it could work for adults.

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Hi Drop-Loud, you’re welcome. I agree with you. Let’s go ahead, we must not abandon hope.

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Quote from: Antoine on September 13, 2020, 11:46:18 PMYou’re welcome Drop-Loud. You’re right, we should find a way to contact them. I‘ll try. If I succeed, I’ll let you know.

Hi Antoine!

Did u find any information about the korean company? if not maybe I can help

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Hi Excited,

This is the website of the Korean company, but they did not answered to my email. I completed the form 2 weeks ago.

Maybe Antoine and you will have more luck 

http://ckbiotech.co.kr/company/locationcontact/

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That's what they plan to treat :

http://ckbiotech.co.kr/business-targets/patents/

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@Drop-Loud & excited

Thank you. I’ll try to contact CKBiotech and let you know.
However, I read on their site these words about the compound: “The small molecule-induced activation of the Wnt/beta-catenin pathway enhances longitudinal bone growth around 10% by prolonged-activation of chondrocytes in the growth plates of the teen under going senescence.” This is note exactly encouraging, but we’ll see.

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Quote from: Antoine on September 14, 2020, 02:32:50 PM“The small molecule-induced activation of the Wnt/beta-catenin pathway enhances longitudinal bone growth around 10% by prolonged-activation of chondrocytes in the growth plates of the teen under going senescence.”

Doesn't senescence mean aging? So here it means fusing growthplates?

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Quote from: O_99 on September 14, 2020, 02:57:18 PM“The small molecule-induced activation of the Wnt/beta-catenin pathway enhances longitudinal bone growth around 10% by prolonged-activation of chondrocytes in the growth plates of the teen under going senescence.”

Doesn't senescence mean aging? So here it means fusing growthplates?

Yes. They claim the compound can delay the fusion of teens’ growth plates (i.e. growth plates that are gonna fuse soon), they don’t claim that the compound can reverse the fusion of growth plates after it’s happened.