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Posted on Sep 14, 2020, 4:59 pm
#121

Maybe Link protein N-terminal peptide (LPP) could work for people with closed growth plates. I'm sure that a drug will be available one day for people with closed growth plates. Unfortunately, researchers are not very interested in helping adults growing taller.

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Posted on Sep 14, 2020, 6:05 pm
#122

Quote from: Drop-Loud on September 14, 2020, 04:59:52 PMMaybe Link protein N-terminal peptide (LPP) could work for people with closed growth plates. I'm sure that a drug will be available one day for people with closed growth plates. Unfortunately, researchers are not very interested in helping adults growing taller.


From what I can understand here,
https://www.reddit.com/r/looksmaxxing/comments/icziqe/an_update/
(this is included in his post: https://www.hindawi.com/journals/sci/2018/3217895/)
he ditched out 'HDAC4 antagonists' for the safer LPP, but did he test it on rats or..?

Doesn't mention anything.


______



https://www.researchgate.net/publication/51368776_Histone_Deacetylase_4_Controls_Chondrocyte_Hypertrophy_During_Skeletogenesis

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Posted on Sep 17, 2020, 10:06 pm
#123

I don't know. I asked the Reddit guy if he still think Indirubin could work for people with closed growth plates after the message written by Prof. Choi of CK Biotech. That's what he said :

Wnt/b-catenin still plays a role in the proliferation of collagen. What we're trying to do s basically treating the knee (few suggested the tibia) joints as a growth plates by controlling cartilage growth and ossification.

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Posted on Sep 17, 2020, 10:06 pm
#124

I don't know. I asked the Reddit guy if he still think Indirubin could work for people with closed growth plates after the message written by Prof. Choi of CK Biotech. That's what he said :

Wnt/b-catenin still plays a role in the proliferation of collagen. What we're trying to do s basically treating the knee (few suggested the tibia) joints as a growth plates by controlling cartilage growth and ossification.

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Posted on Sep 17, 2020, 10:26 pm
#125

So, basically, a no.

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Posted on Sep 17, 2020, 10:26 pm
#126

So, basically, a no.

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Posted on Sep 18, 2020, 3:10 pm
#127

are you retarded man? This LPP method doesn't INVOLVE epiphyseal cartilage anymore, we are now working with joint cartilage and increasing the length of epiphysis (which can be unlimited but it would cause osteoarthritis if the cartilage isn't regenerated back again). Actually take the time to read instead of blabbing on like a little kid. LL surgeries involve increasing length in the middle of the bone, this involves increasing length through the ends of the bones.

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Posted on Sep 18, 2020, 3:19 pm
#128

Can this shiet also happen to work on forearms and humeruses?

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Posted on Sep 18, 2020, 3:21 pm
#129

Look who joined the forum What is the future of limb lengthening? What do you hope to see happen?
Lmao

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Posted on Sep 18, 2020, 3:24 pm
#130

Quote from: Strike_Poseidon on September 18, 2020, 03:10:26 PMare you retarded man? This LPP method doesn't INVOLVE epiphyseal cartilage anymore, we are now working with joint cartilage and increasing the length of epiphysis (which can be unlimited but it would cause osteoarthritis if the cartilage isn't regenerated back again). Actually take the time to read instead of blabbing on like a little kid. LL surgeries involve increasing length in the middle of the bone, this involves increasing length through the ends of the bones.


You can quote the poster you want to call 'retarded'.

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